Get yourself these, or something similar:
Totally worth it. Those larger spring clamps are a bear with pliers or channel locks. Can be done, but these make it better. I still managed to bruise a finger tip by mishandling the clamp. I don't remember exactly what happened, but I am positive it is precisely what Colly did too!
Im sure there are smarter videos on Youtube. But what I did is:
Disconnect the overflow bottle and drain it. Fill and drain it several times to get the old coolant out.
Unhook the lower rad hose. Let the coolant run out. When it stops dripping hook it back up and fill the system with clean water.
Disconnect the heater core hose closest to the engine and let it drain.
run the hose into the radiator
Run the engine and set the heat to full hot so you get flow going through the heater core.
Water will be running out of the heater core, careful it will be hot. It should be being replaced by the hose but keep a close eye on your temp gauge at all times. Run it like that for a few minutes.
Stop the engine, and the garden hose. Hook up the heater core again. Top off the radiator and let the engine run like normal for a few minutes.
When you are sure the thermostat is open and you are getting nice hot air from the vents, shut it off and start over. Unhook the lower radiator hose (Careful it is 190* now) and drain the system..
Rinse and repeat until you are satisfied with the clarity of the water coming out of the system.
Then your last refill will be with distilled water and undiluted DexCool mix. There will be some straight water in your heater core and engine, so filling the system up now with 50/50 will leave you on the shy side. Its a guesstimate. My first gallon going in was 75% coolant 25% distilled. Then I added 50/50 from there. Run the truck for a few minutes to get it all mixed together. Then let it cool for enough time to allow you to safely remove the radiator cap. Use your hydrometer to assess your mix. You will be pretty close, but you can siphon off some coolant mix from the rad (put that into the overflow) and add water or undiluted Dexcool to refine the mix. It may take a couple days to dial it in.
Just be super careful with those spring clamps and the hot water. Wear protective gear, and protect the environment.